Estrogen-Like Activity of Metals in Mcf-7 Breast Cancer Cells 11/05/2011 09:42:23The ability of metals to activate estrogen receptor- (ER) was measured in the human breast cancer cell line, MCF-7. Similar to estradiol, treatment of cells with the divalent met...
Estrogen Carcinogenesis in Breast Cancer 10/05/2011 09:14:14In this article, we review recent findings related to estrogen exposure and the risk of breast cancer, the mechanisms that may be involved, and the clinical implications of these f...
Mitochondria: sovereign of inflammation? 21/03/2011 10:20:33NLRP3‐inflammasome dependent inflammatory responses are triggered by a variety of signals of host danger, including infection, tissue damage and metabolic dysregulation. How ...
Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction. 10/03/2011 07:54:07C Corona, F Masciopinto, E Silvestri, AD Viscovo, R Lattanzio, RL Sorda, D Ciavardelli, F Goglia, M Piantelli, LM Canzoniero, SL Sensi
The overall effect of brain zinc (Zn(2+))...
Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease. 04/03/2011 09:39:21Wilson disease (WD) is a rare hereditary condition that is caused by a genetic defect in the copper-transporting ATPase ATP7B that results in hepatic copper accumulation and lethal...
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma [Medical Sciences] 02/03/2011 05:43:30Bevacizumab, an antibody against vascular endothelial growth
factor (VEGF), is a promising, yet controversial, drug in human
glioblastoma treatment (GBM). Its effects on tumor bu...
Regulation of Mitochondrial GSH [Metabolism]. 13/12/2010 04:18:47Brain and liver mitochondria isolated by a discontinuous Percoll gradient show an oxidized redox environment, which is reflected by low GSH (glutathione) levels and high GSSG level...
Mitochondrial dysfunction in autism 08/12/2010 05:17:54C Giulivi, YF Zhang, A Omanska-Klusek, C Ross-Inta, S Wong, I Hertz-Picciotto, F Tassone, IN Pessah
CONTEXT: Impaired mitochondrial function may influence processes highly depen...
Mitochondrial fusion and fission in cell life and death 25/11/2010 05:20:51 Benedikt Westermann
Abstract
Mitochondria are dynamic organelles that constantly fuse and divide. These processes (collectively termed mitochondrial dynamics) are important f...
Measurement of Intracellular ATP [Cell Biology] 22/11/2010 05:00:14Adenosine 5"-triphosphate is a universal molecule in all living cells, where it functions in bioenergetics and cell signaling. To understand how the concentration of ATP is regulat...