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Artigos

 Laboratory evaluation of estrogen metabolism - Estrogen Metabolism
28/11/2011 06:53:08

Higher levels of estradiol (E2), and especially estrone (E1), in serum and urine have been consisten...

Publicações Científicas

 Estrogen-Like Activity of Metals in Mcf-7 Breast Cancer Cells
11/05/2011 09:42:23

The ability of metals to activate estrogen receptor- (ER) ...
Artigos cadastrados

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice [Medical Sciences] 09/03/2011 10:09:19

A causal role for mitochondrial DNA (mtDNA) mutagenesis in mammalian aging is supported by recent studies demonstrating that the mtDNA mutator mouse, harboring a defect in the proo...

Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells. 04/03/2011 04:31:21

Fine tuning of the protein folding environment in subcellular organelles, such as mitochondria, is important for adaptive homeostasis and may participate in human diseases, but the...

Listeria monocytogenes transiently alters mitochondrial dynamics during infection [Cell Biology] 02/03/2011 05:48:35

Mitochondria are essential and highly dynamic organelles, constantly undergoing fusion and fission. We analyzed mitochondrial dynamics during infection with the human bacter...

Metabolic regulation by p53 01/03/2011 10:12:00

We are increasingly aware that cellular metabolism plays a vital role in diseases such as cancer, and that p53 is an important regulator of metabolic pathways. By transcriptional a...

Estresse oxidativo mitocondrial provoca fragmentação mitocondrial através da modulação diferencial de proteínas mitocondriais fissão / fusão 17/01/2011 03:44:16

Mitochondria are dynamic organelles with continual fusion and fission to maintain their morphology and functions, but the mechanism involved is still not clear. Here, we investigat...

Mitochondrial Dysfunction in Autism 01/12/2010 04:54:34

Context Impaired mitochondrial function may influence processes highly dependent on energy, such as neurodevelopment, and contribute to autism. No studies have evaluated mitochond...

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction. 01/12/2010 04:45:06

S Someya, W Yu, WC Hallows, J Xu, JM Vann, C Leeuwenburgh, M Tanokura, JM Denu, TA Prolla Caloric restriction (CR) extends the life span and health span of a variety of species ...

SIRT3 in Calorie Restriction: Can You Hear Me Now? 01/12/2010 04:40:55

Caloric restriction decreases oxidative damage and extends life span in many organisms. Someya et al. (2010) show that the sirtuin SIRT3 mediates the protective effects of caloric ...

Microbiota intestinal e sua possível relação com a obesidade 17/11/2010 08:47:08

Obesity results from alterations in the body’s regulation of energy intake, expenditure, and storage. Recent evidence, primarily from investigations in animal models, suggests th...

Associações entre hábitos alimentares e índice de massa corporal com composição da microbiota fecal de água intestinal e genotoxicidade 16/11/2010 09:24:11

African Americans (AA) suffer from an increased incidence and mortality of colorectal cancer (CRC). Environmental exposures including dietary habits likely contribute to a high b...

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