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Laboratory evaluation of estrogen metabolism - Estrogen Metabolism
28/11/2011 06:53:08

Higher levels of estradiol (E2), and especially estrone (E1), in serum and urine have been consisten...

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The ability of metals to activate estrogen receptor- (ER ) ...

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Laboratory evaluation of estrogen metabolism - Estrogen Metabolism 28/11/2011 06:53:08

Higher levels of estradiol (E2), and especially estrone (E1), in serum and urine have been consistently associated with a moderately elevated risk of breast cancer. There is some evidence that higher levels of estriol (E3) are associated with a reduced risk of breast cancer. Higher values for the estrogen quotient (E3/E1 E2) have been associated with a reduced risk of breast cancer in some, but not all studies. Many women are seeking alternatives to HRT comprised of conjugated equine estrogens. Popular alternatives include estriol alone or in combination with other natural estrogens. Thus further research on the roles of estriol and the estrogen quotient in assessing breast cancer risk are urgently needed.

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